Kensington Expert Mouse only works on front USB Ports

I have a fairly new Windows 11 Legion Desktop machine. I have been using it since August 2024 with the normal setting up minor issues.
But nothing Major. Anyway, today I booted the machine up and "no Mouse detected". I rebooted and same thing. I have the Kensington
USB Expert Mouse plugged into one of the USB ports in the back of the computer. I tried booting with it plugged into two of the other USB
ports in the back and it still would not recognize the mouse anymore. Plugged and unplugged the mouse in and beep sound but still no mouse.

I then plugged the mouse into one of two USB ports in the front of the computer and it works fine. Works in either of those ports.
I don't know why this all of a sudden happened. No new software or anything. I would like to keep the two front USB ports free if possible for
convenience. Any ideas on what causes a problem like this and possible fix?
Thanks, Dave
Windows version 24H2 (OS Build 26100.3476)

Hi Dave

What’s the exact model? Does it have one on the back? There are a few Lenovo Legion Desktops.

Firstly; Do any other USB devices or USB drives work in the rear USB ports?

If not; Enter your BIOS (press repeatedly, usually F2 or Delete at boot)
Try resetting BIOS to defaults, saving and rebooting.

See if that re-enables the rear USB’s

Check Optional Updates in Windows Update for any updated drivers that may be present.

May sound implausible, but

Unplug PC> Press and hold Power button for 15 seconds (discharge capacitors)> Plug it back in and boot to test operation. Has 100% worked for others with USB issues in the past. An easy thing to test

A Guy