That would not be me, but I'll answer anyway just because I have experimented with this in the pastOne of the smart people here will have to advise.

I had a laptop with a small SSD so my backups would not be terribly large. I tested saving backups to OneDrive and splitting files into smaller chunks and it worked just fine for me. Please note that I didn't make extensive use of this. It was in an experimental stage for me.
Ultimately, what I ended up doing was installing a product called "StableBit CloudDrive". Absolutely brilliant. It mounts your cloud storage as if it is just another local drive in your system with its own drive letter. Plus, it can create a redundant copy of the data on OneDrive (or whatever cloud storage provider you use). Now you can perform your backup as if you are simply going to a local drive and it handles all the details in the background. You can even do stuff like set up caching so you don't have to wait for it to copy everything to the cloud. You can shut down your system and the next time you power it up it will finish transferring data to the cloud.
Personally, I prefer local backups, but as you mentioned, this will provide an off site backup for an additional layer of protection.
My Computers
System One System Two
-
- OS
- Win11 Pro 24H2
- Computer type
- PC/Desktop
- Manufacturer/Model
- Self-built
- CPU
- Intel i7 11700K
- Motherboard
- ASUS Prime Z590-A MB
- Memory
- 64GB (Waiting for warranty replacement of another 64GB for 128GB total)
- Graphics Card(s)
- No GPU - Built-in Intel Graphics
- Sound Card
- Integrated
- Monitor(s) Displays
- HP Envy 32
- Screen Resolution
- 2560 x 1440
- Hard Drives
- 1 x 1TB NVMe SSD
1 x 2TB NVMe SSD
1 x 4TB NVMe SSD
3 x 512GB 2.5" SSD
1 x 4TB 2.5" SSD
5 x 8TB Seagate Barracuda HDD
- PSU
- Corsair HX850i
- Case
- Corsair iCUE RGB 5000X mid tower case
- Cooling
- Noctua NF-S12A chromax.black.swap case fans (Qty. 7) & Home Computer Specifications, Configuration, and Usage Notes General Specifications ASUS Prime Z590-A motherboard, serial number M1M0KC222467ARP Intel Core i7-11700K CPU (11th Gen Rocket Lake / LGA 1200 Socket) 128GB Crucial Ballistix RGB DDR4 3200 MHz DRAM (4 x 32GB) Corsair iCUE RGB 5000X mid tower case Noctua NH-D15 chromax.black CPU cooler Noctua NF-S12A chromax.black.swap case fans (Qty. 7) & Corsair LL-120 RGB Fans (Qty. 3)
- Keyboard
- Corsair K70 Max RGB Magnetic Keyboard
- Mouse
- Logitech MX Master 3
- Internet Speed
- 1Gb Up / 1 Gb Down
- Browser
- Edge
- Antivirus
- Windows Defender
- Other Info
- The five 8TB drives and three 512GB SSDs are part of a DrivePool using StableBit DrivePool software. The three SSDs are devoted purely to caching for the 8TB drives. All of the important data is stored in triplicate so that I can withstand simultaneous failure of 2 disks.
Networking: 2.5Gbps Ethernet and WiFi 6e
-
- Operating System
- Win11 Pro 23H2
- Computer type
- Laptop
- Manufacturer/Model
- Lenovo ThinkBook 13x Gen 2
- CPU
- Intel i7-1255U
- Memory
- 16 GB
- Graphics card(s)
- Intel Iris Xe Graphics
- Sound Card
- Realtek® ALC3306-CG codec
- Monitor(s) Displays
- 13.3-inch IPS Display
- Screen Resolution
- WQXGA (2560 x 1600)
- Hard Drives
- 2 TB 4 x 4 NVMe SSD
- PSU
- USB-C / Thunderbolt 4 Power / Charging
- Mouse
- Buttonless Glass Precision Touchpad
- Keyboard
- Backlit, spill resistant keyboard
- Internet Speed
- 1Gb Up / 1Gb Down
- Browser
- Edge
- Antivirus
- Windows Defender
- Other Info
- WiFi 6e / Bluetooth 5.1 / Facial Recognition / Fingerprint Sensor / ToF (Time of Flight) Human Presence Sensor