A two Up-to-date PCs issue: one PC running Microsoft Windows 10 OS and with Microsoft Office 2021 installed, and the second PC running Microsoft Windows 11 OS and with Microsoft Office 2024 installed.
In fact, the second PC mentioned here is also totally installed from the very scratch just 10 days ago because of a brand new Samsung SSD was putted in this PC...
All in all, on this both PCs everything was perfectly fine just before two days ago and with the older installed Microsoft Visual C++ 2015-2022 Redistributable - 14.36.32532 and which was installed on this both PCs on 16th March 2025.
However, on 23rd March 2025 on this both PCs was installed the newest Microsoft Visual C++ 2015-2022 Redistributable - 14.42.34438.0, and from that moment and on this both PCs I was not be able to start Microsoft Office applications any more at all, because it always brings Something went wrong error window and with the error code 0x426-0x0 .
I further discovered that the main problem is that the Microsoft Office Click-to-Run Service is all of a sudden not engaged on this both PCs, so I try to run it, but it brings another Error 1053, that it could not start, that the service did not respond to the start of control request in a timely fashion.
I also try to go to Programs and Features to try to (not Uninstall), but to Repair the Microsoft Office on both of this PCs, but on both of them when you press this Repair option here, absolutely nothing is happening, like I did not engage it/press it at all...
I also try all above mentioned, after I restart both of this PCs, and I also run ScanHealth, CheckHealth, RestoreHealth, SFC/SCANNOW, and everything reported just perfectly fine and without any errors whatsoever.
However, I did not yet try to completely Uninstall both Microsoft Offices here, I am even afraid now, that even the regular Uninstall option is also break here..., so dear Microsoft Corp. congratulations on your "beautiful" mess again.
I am reporting this here to warn others on caution of this nightmare scenario possibility to happen also on their PCs!!!
And I am reporting this also here, if someone has any other idea whatsoever that I can also try here, before I try just the regular and full Microsoft Office Uninstall option here, and if that option will not react when I press it at all (like the Microsoft Office Repair option did not either), then I do not know..., I will try an unofficial desperate Uninstall procedure then here, the Abbodi1406 - OfficeScrubber v13 (released on 18 September 2024) instead.
Finally, I will update this Forum thread even further, when and how I will finally resolve this problems of this both PCs...
Thanks for any help and suggestions in advance to anybody on this great Forum and best regards to all here!
In fact, the second PC mentioned here is also totally installed from the very scratch just 10 days ago because of a brand new Samsung SSD was putted in this PC...
All in all, on this both PCs everything was perfectly fine just before two days ago and with the older installed Microsoft Visual C++ 2015-2022 Redistributable - 14.36.32532 and which was installed on this both PCs on 16th March 2025.
However, on 23rd March 2025 on this both PCs was installed the newest Microsoft Visual C++ 2015-2022 Redistributable - 14.42.34438.0, and from that moment and on this both PCs I was not be able to start Microsoft Office applications any more at all, because it always brings Something went wrong error window and with the error code 0x426-0x0 .
I further discovered that the main problem is that the Microsoft Office Click-to-Run Service is all of a sudden not engaged on this both PCs, so I try to run it, but it brings another Error 1053, that it could not start, that the service did not respond to the start of control request in a timely fashion.
I also try to go to Programs and Features to try to (not Uninstall), but to Repair the Microsoft Office on both of this PCs, but on both of them when you press this Repair option here, absolutely nothing is happening, like I did not engage it/press it at all...
I also try all above mentioned, after I restart both of this PCs, and I also run ScanHealth, CheckHealth, RestoreHealth, SFC/SCANNOW, and everything reported just perfectly fine and without any errors whatsoever.
However, I did not yet try to completely Uninstall both Microsoft Offices here, I am even afraid now, that even the regular Uninstall option is also break here..., so dear Microsoft Corp. congratulations on your "beautiful" mess again.

I am reporting this here to warn others on caution of this nightmare scenario possibility to happen also on their PCs!!!
And I am reporting this also here, if someone has any other idea whatsoever that I can also try here, before I try just the regular and full Microsoft Office Uninstall option here, and if that option will not react when I press it at all (like the Microsoft Office Repair option did not either), then I do not know..., I will try an unofficial desperate Uninstall procedure then here, the Abbodi1406 - OfficeScrubber v13 (released on 18 September 2024) instead.
Finally, I will update this Forum thread even further, when and how I will finally resolve this problems of this both PCs...
Thanks for any help and suggestions in advance to anybody on this great Forum and best regards to all here!

My Computer
System One
-
- OS
- Microsoft Windows 11
- Computer type
- PC/Desktop